??????å·?æ³½ç?????©å?¶è???¡ä»½???????¸ï?æ³½ç???¶è????688266.SHï¼????家ä?注ä??¿ç?¤ã???ºè???è¡?液ç?¾ç?????????????§ç?¾ç?????????¾ç??ç­?å¤?ä¸?²»??é¢????????°è??????????产å???????????°å?????©å?¶è???ä¸???2020å¹???ï¼?æ³½ç???¶è???¨ç????¿æ????ä¸?å¸?ï¼???ä¸??¡å??ºä?é¦?家以ç§????¿ç?äº?å¥?????å®???POä¸?å¸??????¸ï????¶äº¦??为å?½å??èµ?????ºæ³¨???¶æ?¹é?©ç??è§?è¯?人ã??

????????ç«?以æ?¥ï????¸ä??´ç??¿å???°é©±?¨ã?????????????念ã???¹æ?????ä¿¡æ??????¸ç?????¥æ??两个?°è?????¶æ?¸å?????¹³?°ï??³å???å­????©ç??????产ä???å¹³å?°ã??å¤?????ç»????½ç???©æ?°è??????ä½??°è????????产ä???å¹³å?°ï?并å?ºä?æ­¤ç?????ºä?ä¼?å¤???ç£?产å??ï¼??????纳é??å°¼ç?????°å???¿å°¼????ZG19018??????ç»?人å??è¡??¶å??注å??¨é??ç»?人ä??²ç?¶è?ºæ?ç´?ç­?ç­???æ­¤å?ï¼?ä¾???ç¾??½å?????ENSUN??TriGen??CheckGen??TGenç­?ä¸?ä¸????°æ??ä½????©ç????å¹³å?°ï????¸è??¸»????äº?ä¸?ç³»å???·æ??ä¸??©ä??¤ç????/ä¸??¹å???ä½???产å??管线ï¼???åº???è¦???????????å°?ç»????ºç????ç»??´è???????²ç?¶è?ºç????骨é?å¢?æ®??§ç?¾ç??ç­??¶æ?§è?¿ç?¤ï?以å???ºè????????¾ç??????º«?????§ç?¾ç??ç­?å¤?ä¸?²»??é¢?????

?????¹æ?????ä¿¡æ????°å???¿å°¼????ç»?人å??è¡??¶ç?å¤?ä¸??¸å?产å????å¤?ä¸???åº???????äº?2023å¹´è?·æ?¹ï???年磨ä¸???ï¼?æ³½ç???¶è???å¹´ç?????????¥å?³å?è¿??¥æ?¶è?·æ????????人士???ºï???»¥é¢?è§?????????????¸å???°è???©é??ç»???¥å??ä¸????¶æ?ï¼?????????????ç»??线ç??ä¼??¿ï????¸å?稳æ?è·µè??????¿ç?¤å????????å­??¶å??????æ²»ç??产å??ä½?ç³»ç?????¥ç????ï¼?ä¸?绩ä?å°???ä¹?è¿??¥â??????å¼???å¢??¿ï???????为å??°å????¥æ?¶ç??é«????¿å???°å???»è???ä¸?ï¼???为注???¶æ?¹é?©æ??绩簿ä¸???????注è????

???????????°é©±?¨ç????????æ¶?? ??ä¸????½å??ä¸???????

????æ³½ç???¶è??????ç«?以æ?¥å°±å»ºç?äº???究å??å¼????·æ????¸»?¥è?产æ????å®??¨ã?????????£è????????????°è???©ç?????¥ç???????¨ç??????注é???¿ç?¤ã???ºè???è¡?液ç?¾ç?????????????§ç?¾ç?????????¾ç??ç­?é¢???ï¼?å¡?¡¥?½å??空ç?½ï?为å???»¡è¶³ç??临å???æ±???ä¾?æ²»ç?????©ã???¹æ?????èµ???ï¼????¸å?????¿æ??äº?5项å?½å?????大æ?°è?????¶â????1项å?½å?ç§?????ä¸??ä¼?ä¸????????°å?ºé????å¤?项æ?????级ç???项ç???????022å¹???30?¥ï????¸æ?¥æ??å·²æ????????ä¸???13项ï????????ENSUN 9项ï?ï¼?ç´???³è?????ä¸???81项ï????????ENSUN 38项ï???

?????¹æ??³½???¶è??????ä»?ç»?ï¼????³ç????ï¼????¸å·²??å¤?纳é??å°¼ç??ä¸?线治????????ç»???????è¿?å±??§ã??å±??¨æ??????è½?§»?§æ?¾å??§ç??¾æ²»?§å???????²ç?¶è?ºç??2ä¸???åº????·æ?¹ä?å¸?ï¼??þ@??°å???¿å°¼??????ç»?人å??è¡??¶å??注å??¨é??ç»?人ä??²ç?¶è?ºæ?ç´?3ä¸???????8项é??åº???å¤?äº?ä¸?å¸??³è???III????注å??临å??¶æ???

?????¶ä¸­ï¼?å¤?纳é??å°¼ç????¸­?½å?¶è???ä¸?????ä¸?å¸???ç¬??ä¸??线治????????ç»???????å°???å­??¶å?????°è???©ï?ä¹???????为æ????ä¸?ä¸??????ç´¢æ????尼头对头对ç??II??临å?è¯?éª???å¾?ä¼??????°è???????½æ????????é«????½å?ï¼?é¢?计å??025å¹´ï????½ç????ç»?????????人æ?°å?å¢?????7.5ä¸?人ï??¨ä¸­?½å·¨å¤§ç??????å¸??ºä¸­ï¼?å¤?纳é??å°¼é?????ä¸?线治??ç«?äº?ä¼??¿ä?使å?该è??¤§????¸º??æ­¤å?ï¼?å¤?纳é??å°¼ç???²ç?¶è?ºç????åº???以å?????¸æ??¨ç§¯??å¼?å±???ä¸???PD-1/PD-L1??ä½????¿ç?¤è????æ²»ç??åº????å°?è¿?ä¸?æ­¥ä?è¯?å¤?纳é??å°¼æ?¥æ???????å¸??ºç©º?´ã??

?????¤å?纳é??å°¼å?ï¼????¸ç????ä¸???ç£?产å???°å???¿å°¼??å·²æ??å¤?项ä??¿é??åº?????ç»???å¾?çª??´ï??¶ä¸­æ²»ç??骨é?纤维????åº?????ä¸?å¸??³è?å·²è?·å????ï¼???????为ç?ä¸?ä¸??·æ?¹ä?å¸????½äº§JAK???¶å??ç±?est-in-Class???°è???©ã???¤é?é«?纤维??å¤?ï¼??°å???¿å°¼è¿??·å??¨å?????????§ç?¾ç??ä¸????´å¹¿æ³???临å?åº??¨æ??????¹æ??³½???¶è??????ï¼?æ³½ç???¶è????¨å?å±??????¨æ?°å???¿å°¼??æ²»ç????????ç§???ä¸???åºþ>?¹å??§ç??????强ç?´æ?§è???±ç??ç­???åº?????III??临å?è¯?éª?ï¼?以å??å¤?项å?????????§ç?¾ç????II??临å?è¯?éª????¹æ??ncyte以å??诺å???????ä¿¡æ????°å???¿å°¼??ç«????þ@???¿å°¼2022å¹´ç???¨ç????????é¢?é«?è¾¾è?40亿ç???????对é?é«?纤维????åº???ï¼??´ä??°å???¿å°¼?¨ä¸´åº?è¯?éª?ä¸?·²å±??°å?ºä?äº??þ@???¿å°¼???²æ?°æ????????ï¼?å¸??ºæ?????±å??¶æ???¥é?????模ç?äº?è¾?大æ??å¾???

????å¤??¨é??ç»?人å??è¡??¶æ?å¤?äº?BLA审è?è¿?ç¨?ä¸?????????½å????????¨é??ç»??ºå????????产ã??å¼?å±?III??临å?è¯?éª?并è?·å?è¯?éª???????产å??ï¼??¸è?äº??¶ä????©æ?¥æ?æ­¢è?????ï¼??¶å?·æ???¹å??§æ?´é???æ­¢è?????é«????ºè???大å???å°???ä¼??¿ï????¶å???????§å??????ç­?é£??©ä??´ä????¤æ?ä¹?å¤?ï¼?????????ç»????½å·¥?ºå??»¥å®??°å¤§è§?模æ???????§ç????ä¸?????产ï??¸è?äº??´æ?¥ä?è¡?æµ?ä¸??????????´ä???ä¸???人士???ºï????½å?ç§?æ­¢è????©å??ºç©º?´å¹¿??ï¼?2020å¹´å?ç§??????°æ?°ä¸º6324.6ä¸??°ï?é¢?è®?025å¹´å?è¾¾å??0110.3ä¸??°ï?2020å¹´å?ç§???????¨æ?è¡????©å??ºä¸º70.7亿å??ï¼?é¢?è®?025å¹´å?è¾¾å??23.5亿å?????±ä?å¤??¨é??ç»?人å??è¡??¶æ????å®??¨å?????????§ç??产å???¹å?ï¼??¶å????½æ?¿ä»£?¨ä?å¤?ç§???????¨æ?è¡???ä¼?ç»????©è????ï¼?å¸??ºæ???大ï?????å¡?¡¥?½å??å¸??ºç©º?½ã??

????æ­¤å?ï¼?注å??¨é??ç»?人ä??²ç?¶è?ºæ?ç´?ï¼?rhTSHï¼?2ä¸?II??临å?è¯?éª?æ­£å?¨è?è¡?ä¸????¸­?½é??¹å??å¾??¨ä??²ç?¶è?ºç????è¾??©è?????æ²»ç??临å?è¯?éª??¹ä»¶???°è?????¹æ?????ä¿¡æ???????ä¸??½å??ºä?å°???????ç»?人ä??²ç?¶è?ºæ?ç´?产å??ï¼?对å?å¸??ºå?äº?空ç?½ç?¶æ??ï¼??½å?ä»???èµ?诺è?²ï?Sanofiï¼????¸ç??Thyrogenä¸?å¸????????±ä?ä¸??½ç?²ç?¶è?ºç??æµ?è¡???å­þ>??å¿?????å±??????¥å??¥ç??æµ?ä¸?è¾??©æ²»????巨大??æ±?ï¼?rhTSH??????为ä?ä¸????¨ä???????¥½???²ç?¶è?ºç????è¾??©è?????è¾??©æ²»?????©ï????©ä?ä¿?è¿?è¡?ä¸?æ²»ç????????建ç???ä¼???ï¼?å¡?¡¥?½å??å¸??ºç©º?½ï?满足???½ç?²ç?¶è?ºç??æ²»ç????è¯?????临å???æ±?ï¼?ä»???è¿?ä¸?æ­¥æ??é«??²ç?¶è?ºç???£è?????¿æ????å­?????

????ä¸?注ä?大å??ä¸??¸å? ??建è?¿ç?¤å????????å­??¶å??????æ²»ç??产å??ä½?ç³?/p>

????ç»?è¿?å¤?å¹´è???þ@??å±?ï¼?æ³½ç???¶è??·²??步形???¿ç?¤å??è¡?液ç?¾ç?????ºè?????伤é???ï¼?以å???????????§ç?¾ç??ä¸?大ç????????ä¸????¿æ?¸å?é¢?????

?????¨æ?°è??????é¢???ï¼?æ³½ç???¶è??§¯??è·µè????°å??å­þA??????°ç???©è??¹¶é©¾é?驱ç?????¥ã??æ³½ç???¶è???¨è?¿ç?¤æ?°è???å±??¹é?¢æ³¨???¿ç?¤å????²»?????¿ç?¤å¾®?????å­??¶å??æ²»ç????å¤?å±?次è????ï¼?ç³»ç??§å??å±??¨ç?¹å??§æ???¿ç?¤ç?¸ç???ï¼?大å??å­???å°???å­?????ç­??¥ç????å±?ï¼???建è?¿ç?¤å????????å­??¶å??????æ²»ç??产å??ä½?ç³»ã???¤è?ä¸?æ­¥å?å±??°ä?代ã???¨æ?°å??å­??¶å??å°???å­???å­þ=?°è???ï¼????¸è????ç¾??½æ?§è?¡å?????ENSUN????究æ????ï¼?ç§???å¼????·æ???¨ç??é¢????§å??ç«?äº?????ç³»å?????¿ç?¤æ??ä½??°è??º§??ï¼??????ä¸???/ä¸??¹å??§æ??ä½?ZG005??ZGGS18??ZG006??GS11??ZGGS15??ZGGS001ç­????¶ä¸­ZG005?¨ä¸­?½ç??I/II??临å?è¯?éª?å·²ç????¨å¹¶å·²è??DA??临å??¹å??ï¼?注å???GGS18å·²è?·å?NMPA??FDA??临å??¹å??ï¼?ZGGS15??IND?³è?å·²è??MPA????ï¼?é¢?计å?ä¸???ä½?产å??å°?äº?2023å¹´ç?³æ?¥ä¸­?½å??ç¾??½ç??IND???????¥æ??å·????ç«?äº?ä¼??¿ç??产å??管线????æ­¥æ?©å?ï¼????¸è??¥ä??¿ç?¤å????²»????ç«?äº??µå?ï¼?为å??°å???¸â??å°???å­??¶å???°è???¿ç?¤å??????æ³?????????æ²»ç?????¥å¤¯å®??ºç?ï¼?ä»??????¥å???¸å???å­??¶å???°è?????°ä?代æ??ä½?产å??管线??????ä¼??¿ï?ä¿?è¯????¸å?¨æ???¿ç?¤è???©ç????é¢???????ç»??äº?????é¢????°ä?ï¼?ä¹?为å???¸æ???¥å?¨å?½å??å¤?å¤?ç»´æ???¥å??ä½???ä¾?äº?强æ???????ºç???

????ä¹?注å???¶æ?¹é?©ä?é£? ???©è?????ºè?????å±??°çºª??

????æ³½ç???¶è???¿æ??以æ?¥ç?足è??¸»????ï¼?追æ???è¶?ï¼?ä»?ä¸?å¸?????29项å?¨ç??项ç???°ç??????è¿?50项主è¦??¨ç??项ç???2022年度é¢?计å??°è?è¿?3亿å???¶å?¥ï?ä»???ä¸?å¸?产å???°å?³å??¥æ??è¶?è¿?3ä¸??å¸?产å????å¤?ä¸???åº????·æ?¹ï?注å???¶æ?¹é?©å??ç§????¿è?è¯?äº????¸è?å¹´æ?¥ç?é£???è¿?????å±???

????????人士认为ï¼??¸ä¿¡???¥é???????¸ç????å®?????è¿?ä¸?æ­¥æ???????¨ç??管线????ç»??¨è?ï¼?以å???¿ç?¤å????????å­??¶å??????æ²»ç??产å??ä½?ç³»ç??建ç?ï¼?æ³½ç???¶è???è¿?ä¸?步践è¡???å¸??ºä¸ºå¯¼å???????????°ä¸º?¸å??????¡æ?£è??为å??¨â??????念ï??¨æ??ç»?¸º?¡ä?????ä»·å?¼å??满æ?????¥ç?????¶ï?äºþ@?¨æ?´å??广æ?????大ç??æ²»ç??é¢???满足?£è????临å???æ±?ï¼???????为å?·å?综å??ç«?äº?å®?????Biopharmaä¸?????è¿???